The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals. The AOP framework and associated knowledgebases (KBs) have received significant attention and use in the regulatory toxicology community. However, it is increasingly apparent that the potential stakeholder community for the AOP concept and AOP KBs is broader than scientists and regulators directly involved in chemical safety assessment. In this paper we (...) identify and describe those stakeholders who currently—or in the future—could benefit from the application of the AOP framework and knowledge to specific problems. We also summarize the challenges faced in implementing pathway-based approaches such as the AOP framework in biological sciences, and provide a series of recommendations to meet critical needs to ensure further progression of the framework as a useful, sustainable and dependable tool supporting assessments of both human health and the environment. Although the AOP concept has the potential to significantly impact the organization and interpretation of biological information in a variety of disciplines/applications, this promise can only be fully realized through the active engagement of, and input from multiple stakeholders, requiring multi-pronged substantive long-term planning and strategies. (shrink)

ABSTRACT While the concept of “infinite distance” (ID) appears as such only in the work of Maurice Blanchot, in this paper we argue that it could be productively coined in Walter Benjamin’s as well. We argue that (1) the concept of ID is elaborated from a revision, a re-signification, and a radicalization of the modern concept of “aesthetic distance”, and that (2) this modification is fundamentally based on the interpretations that both, Benjamin and Blanchot, make first of early German (...) Romanticism, and second of the work of Franz Kafka. This modification, we contend, (3) contains a shift in the ground of the concept: the concept of ID has no longer as ground the realm of the subjective faculties (i.e., the ‘judgment of taste’), but the realm of art and language. Finally, we show (4) that the concept of ID presupposes the existence of a ‘fragmentary impulse’ within literary works that can be understood as a “limit-experience” for the subjectivity. (shrink)

This article retraces the main instances at the root of Merleau-Ponty’s project of a « transcendental geology », a project announced in a working note of 1960. This project is linked to the complex intertwining of history and nature, which Merleau-Ponty thematizes as the two non-objectifiable dimensions that pose a challenge to reflexive thought. History and nature, both in their particular subjective manifestations as personal life or one’s own body, as well as in their broader sense as the history of (...) peoples or nature as a domain of the unbuilt, are characterized as unavoidable, as quasi-objects that are the soil of existence. It is in this direction that Merleau-Ponty’s interest in the “ultra-things” of Henri Wallon, those entities that the child can neither conceive nor imagine, seems to be heading. I propose that ultra-things are linked to inhabiting: they are the uninhabitable and the dimensions that cannot be renounced. This relationship with inhabiting restores the relational aspect of the problem of the unreflective in Merleau-Ponty and highlights the timeliness and urgency of the program of a transcendental geology as an ecology of thought and as an ecological philosophy. (shrink)

La recherche historique dans le cours du dernier demi-siècle a amélioré notre connaissance des mathématiques de I 'Antiquité. Les textes en provenance d'Égypte et de Mésopotamie ont été mieux compris et leur interprétation a dépassé l'alternative sommaire entre empirisme et rationalisme. Le panorama offert par la science grecque s'est enrichi et diversifié: il n'est plus possible de le réduire à la seule théorie géométrique. Les principaux problèmes que posait son histoire ont été l'objet de discussions approfondies. À partir de là (...) des questions plus générales d'ordre épistémologique et philosophique sont soulevées. Y a-t-il un sens à chercher dans un lointain passé une « origine » unique des mathématiques? Quel rapport y at- il entre la forme des mathématiques dans une civilisation et la structure de la société? L'anthropologie culturelle peut-elle aider à interpréter la diversité et l'unité des mathématiques des divers peuples? À partir de quand et sous quelles conditions une histoire unique des mathématiques peut-elle commencer? (shrink)

This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections (...) in the preservation process, and hope you enjoy this valuable book. ++++ The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to ensure edition identification: ++++ Les DEbris De La Guerre; BibliothEque Charpentier Maurice Maeterlinck Fasquelle, 1916 History; Military; World War I; History / Military / World War I; World War, 1914-1918. (shrink)

1. Introduction, par F. Best et al.--2. Histoire de la pédagogie, par Janine Assa et al.--3. Pédagogie comparée, par J. Auba et al.--4. Psychologie de l'éducation, par D. Lavenu et al.--5. Psychologie pédagogique, par F. Beaufils et al.--6. Aspects sociaux de l'éducation, par I. Berger et al.--7. Fonction et formation des enseignants, par F. Amiel-Lebigre et al.--8. Éducation permanente et animation socioculturelle, par P. Besnard et al.

1. Introduction, par F. Best et al.--2. Histoire de la pédagogie, par Janine Assa et al.--3. Pédagogie comparée, par J. Auba et al.--4. Psychologie de l'éducation, par D. Lavenu et al.--5. Psychologie pédagogique, par F. Beaufils et al.--6. Aspects sociaux de l'éducation, par I. Berger et al.--7. Fonction et formation des enseignants, par F. Amiel-Lebigre et al.--8. Éducation permanente et animation socioculturelle, par P. Besnard et al.

(*) Este es el capítulo 16 de su obra monumental titulada Retrying Galileo, 1633-1992, publicado en el 2005 por la University of California Press, Berkeley. Este libro es un examen del affair Galileo desde el momento de la condena del científico toscano por la Inquisición en 1633, hasta su supuesta rehabilitación por el Papa Juan Pablo II en 1992. Su enfoque es en temas tales como: si acaso la condena fue justa, y si probaría la incompatibilidad entre ciencia y religión; (...) pone énfasis en los textos que constituyen las fuentes primarias, y de los cuales emergen los hechos históricos y los distintos temas controversiales. El capítulo 17 del mismo estudio del profesor Finocchiaro, contiene una evaluación precisa, realista y balanceada, de los esfuerzos del Papa Juan Pablo II para poner a la Iglesia al día frente al caso Galileo, conjuntamente con una estimación negativa tanto de la comisión papal encargada de su reexamen, como de su presidente, el Cardenal Paul Pourpard. La traducción es de Hermes H. Benítez, y ha sido expresamente autorizadapor la editorial. (shrink)

Introduction, by R. Peters and M. Cranston.--Hobbes: the problem of interpretation, by W. H. Greenleaf.--Warrender and his critics, by B. Barry.--Hobbes and the just man, by K. R. Minogue.--Hobbes on the knowledge of God, by R. W. Hepburn.--The context of Hobbes's theory of political obligation, by Q. Skinner.--The economic foundations of Hobbes' politics, by W. Letwin.--Hobbes & Hull: metaphysicians of behaviour, by R. Peters and H. Tajfel.--Hobbes on power, by S. I. Benn.--Liberty, by J. W. N. Watkins.--Man and society in (...) Hobbes and Rousseau, by P. Winch.--On the intention of Rousseau, by L. Strauss.--The social contract and Rousseau's revolt against society, by J. McManners.--On le forcera d'être libre, by J. Plamenatz.--Rousseau's images of authority, by J. N, Shklar.--The notion of time in Rousseau's political thought, by W. Pickles.--The structure of Rousseau's political thought, by R. D. Masters.--Rousseau and the problem of happiness, by R. Grimsley.--Individual identity and social consciousness in Rousseau's philosophy, by J. Charvet.--Rousseau's theory of the forms of government, by B. de Jouvenel.--Bibliography (p. [498]-505). (shrink)

Este artículo trata de investigar si es posible que se produzca una emoción partiendo solo de su expresión, y no de un estímulo. Para ello se analizarán algunos trabajos de autores como William James, Francisco Alcayde y Vilar o la psicóloga chilena Susana Bloch. Todos ellos han tratado de demostrar que la expresión de una emoción puede conducir al sujeto a experimentarla. Sin embargo, estas tesis cometen el error de abolir el pensamiento del sujeto, otorgándole una especial importancia a la (...) parte física que diferencian de la que podríamos llamar la parte mental. This article intends to investigate whether an emotion can be born from their expression, and not of an external stimulus. For this reason, I will analyze some works of authors such as William James, Francisco Alcayde and Vilar and Susana Bloch. All of them have tried to show that the expression of an emotion leads a person to experience that emotion. However, these theories are not correct because they invalidate the thinking of the self, and they give special importance to the physical part which they distinguish from what we might call the mental part. (shrink)

Se dice que el utilitarismo es incompatible con la defensa de los derechos humanos, pues la búsqueda del mayor bien para el mayor número que prescribe el utilitarismo, puede exigir, en ocasiones, pasar por encima de los derechos. Sin embargo, quizá sea posible ofrecer una solución al conflicto presentando una doctrina utilitarista, reconocible como tal, que sea lo suficientemente amplia como para dar cabida a los derechos. La presente obra tiene como objeto exponer la doctrina de John Stuart Mill como (...) buen ejemplo de cómo es posible llevar a cabo esta tarea. (shrink)

Principalement dans Procès et réalité, mais aussi dans « Le concept de nature » , dans « Le symbolisme », etc., Whitehead fait de la perception une modalité de la vie. Mais il en distingue deux genres. D'une part, c'est la perception qui, sur le mode de la causalité efficiente, assure la continuité vitale, émotionnelle, du processus de préhensions successives des entités actuelles (mais ce mode perceptif est flou, obscur, puisque ces préhensions sont « des éléments primitifs de notre expérience (...) »). Mais, d'autre part, le second mode de perception, celui de l'immédiateté de présentation, nous donne une vision claire et distincte d'une petite région de notre « monde contemporain » ; son importance tient au rôle qu'il joue dans la constitution des sciences. Mais finalement c'est le rapport symbolique qui nous fournit une perception complète, bien que sujette à l'erreur, par référence d'un mode perceptif à l'autre. Mainly in Process and Reality, but also in « The concept of nature », in « Symbolism », etc., does Whitehead turn perception into one of life's modalities. But he delineates two kinds : on the one hand, perception, in the pattern of an efficient causality, guarantees the vital, emotional continuity of the process of successive prehensions of present entities (but such a perceptive mode is blurred, obscure, since these prehensions are « primitive elements of our experience ». But on the other hand, the second perception mode, i.e. that of immediacy of presentation, grants us a clear and distinct vision of a small area of our « contemporary world » ; its importance derives from the part it plays in the constitution of sciences. But, when all is said, it is the symbolical relationship which grants the true complete perception, though liable to error, with reference from one perceptive mode to the other. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 115 and on a "philosophie de 1'esprit." But he became increasingly interested also in a secular, but non-political, philosophy of religion, which might serve to unite his Platonic idealism and his theory of values. This he formulated in terms of a course of lectures on theodicy, a theodicy closer to Kant than to Leibniz (p. 204). He explained: Notre Th6odic& n'aura pour but ni d'&ablir, ni de (...) r6futer le panth6isme, mais de prouver qu'il exprime fid61ement le contenu de la conscience, et de nous faire sentir par 1~le besoin d'une croyance qui le ddpasse (p. 195). Without cosmology, without ecclesiasticism, it was God's own being that concerned him. "Au fond, comme le voulait Malebranche, nous voyons peut-&re Dieu en lui-m~me" (p. 196). "Dam le peu que j'ai fait, j'ai voulu rester fidble aux grandes pens&s de la philosophie &ernelle qui est la philosophie de l'esprit" (p. 216). HERBERTW. SCHNEIDER Claremont, Calilornia The Phenomenological Movement: A Historical Introduction. By Herbert Spiegelberg. (The Hague: Martinus Nijhoff [Phaenomenologica 5 and 6], 1960. 2 vols. Pp. xxxii + 735.) Professor Spiegelberg's historical introduction to the phenomenological movement is a critical as well as expository effort to trace the development of phenomenological philosophy, taking the work of Edmund Husserl as central to the entire enterprise but also giving serious consideration to his predecessors, associates, and successors. The result is not only an account of phenomenology but an introduction to phenomenological philosophizing. The reader is swiftly caught up in two currents: he may study the history of phenomenology through the chapters devoted to its major representatives, but he may also concern himself with the systematic problems which phenomenologists have encountered and articulated in their careers. The two, of course, are integral, and they are treated that way here. The emphasis, however, is on the phenomena. Even where the discussion is directed toward reporting the reports of others, the stress is still on the "things themselves." In this sense, the history presented here is not merely "about" phenomenology but itself within the horizon of phenomenological procedure. As history, it tells the story of phenomenology; as phenomenology, it reflects upon the phenomena which history recounts. This double stress is evident throughout the two volumes and underlies the purpose of the undertaking as described by the author: 116 HISTORY OF PHILOSOPHY (I) to give a conspectus of the whole range of the Phenomenological Movement, not only of Husserl's part in it; (2) to help understand the background and the reasons for the phenomenological "teachings" in terms related to today's AngloAmerican philosophizing; (3) to take account of, and wherever possible to clarify or answer, the more significant misunderstandings and criticisms of phenomenology (p. xxvi). A quick survey of the contents of the work may be helpful before turning to critical considerations. In his introduction of Volume I, Professor Spiegelberg attempts to state the criteria in terms of which a philosopher is to be considered a "phenomenologist " and his contributions to be taken as part of the subject matter of a history of the phenomenological movement. First, there must be "explicit or implicit adoption by the would-be phenomenologist" of the methods of "direct intuition... as the source and final test of all knowledge, to be incorporated as faithfully as possible in descriptions" and "insight into essential structures as a genuine possibility and a need of philosophical knowledge." Second, there must be "conscious adherence, however qualified, to the Movement as such in full awareness of these methodical principles" (p. 6). The Movement itself is conceived of as a dynamic development from a commonly shared point of departure toward interrelated ends. Movement in this sense does not mean School. The operative criteria are selective enough, however, to enable the author to decide between genuine and pseudo phenomenologies. There then results the inclusion of those figures in the history of philosophy who have either prepared the way for phenomenology or who have carried out genuine phenomenological work. The first volume includes major chapters on Brentano and Stumpf, some ninety pages on Husserl himself, a sizeable section entitled "The Older Phenomenological Movement" which treats the G6ttingen Circle and the Munich Circle (including... (shrink)

La clase de filosofía, desde la perspectiva del docente, no debe considerarse como una mera actividad transeúnte o predicamental. El presente estudio quiere examinarla, siguiendo la metafísica de la vida de Tomás de Aquino, como una obra vital, que requiere, por un lado, que el profesor se haga una sola cosa —una sola vida, podemos decir— con la doctrina que va a explicar y, por el otro, que esta intelección actual, sin movimiento alguno, dé lugar a la «concepción» y al (...) «parto» de lo entendido en una palabra del corazón, la cual, por su dinamismo intrínseco, tiende, a su vez, a manifestarse exteriormente en una palabra sonora, en un «verbum vocis». Esta exteriorización, por la cual aquella íntima operación que constituye la vida del que filosofa se corporeiza en forma de «diálogo», es, precisamente, la clase de filosofía. La técnica pedagógica debe tener en cuenta el orden intrínseco por el cual la vida humana, mediante la formación de una palabra del corazón, procede a su propia perfección, y no debe olvidar que el perfeccionamiento vital del profesor es causa (instrumental) del perfeccionamiento vital del alumno; es decir, quien no «produce», quien no «engendra», quien no «crea» interiormente lo que está explicando —independientemente de si se trata o no de una novedad— difícilmente ofrecerá unos medios adecuados para que el alumno conciba y dé a luz, en la intimidad de su mente, a un «verbum cordis». (shrink)

In 1635 a Latin translation was published of Galileo's Dialogue on the Two Chief World Systems , which had occasioned his condemnation by the Inquisition in 1633. The Latin translation bore the title Systema Cosmicum. It had been organized by Elia Diodati , a Protestant of Italian origin born in Geneva and living in Paris, where he was a Parliament lawyer. Diodati, a confidante of Galileo, had gone into action after receiving a letter that may be regarded as Galileo's intellectual (...) testament, written the same day his legal testament was registered and he decided to journey from Florence to Rome to stand trial. Galileo's letter stated that “from reliable sources I hear the Jesuit Fathers have managed to convince some very important persons that my book is execrable and more harmful to the Holy Church than the writings of Luther and Calvin.”The translator was Mathias Bernegger , the Austrian‐born Protestant rector of the University of Strasbourg, who taught history and political science but had a background in mathematics. The publisher was the influential Dutch firm of the Elseviers, based in Leiden but with branches in several cities. The place of publication was Strasbourg, which at that time was a free city within the Holy Roman Empire. The book had two appendixes: a five‐page selection from Kepler's introduction to his Astronomia Nova , arguing that Scripture carries no weight in natural philosophy; and a Latin translation of Paolo Foscarini's 1615 booklet that had been condemned and banned by the Decree of the Index of 5 March 1616 for arguing that the earth's motion is compatible with Scripture. The book's frontispiece reproduced the one from the original edition—that of Aristotle, Ptolemy, and Copernicus engaged in conversation—but with the figure of Copernicus looking much younger than the original. And the title page carried two epigraphs: a Greek quotation from the Platonist philosopher Alcinous meaning “One must be mentally free if one wants to become a philosopher” and a Latin quotation from Seneca meaning “It is especially among philosophers that one must have equal liberty.”A year later , there appeared also in Strasbourg with the Elseviers and edited by Bernegger the first publication ever of Galileo's “Letter to the Grand Duchess Christina,” which he had written in 1615. It had both the Italian text and a Latin translation by Diodati and bore the revealing title Nov‐antiqua Sanctissimorum Patrum et Probatorum Theologorum Doctrina de Sacrae Scripturae Testimoniis, in Conclusionibuis mere Naturalibus, Quae Sensata Experientia et Necessariis Demonstrationibus Evinci Possunt. It had a preface in which Diodati praised Galileo's astronomical accomplishments, blamed his trial on jealous rivals, and justified the depth and purity of his piety and religiousness. Diodati used the pseudonym Robertus Robertinus, which corresponded to the name of a Prussian poet named Robert Roberthin .These are some of the factual details in Nonnoi's book. Other chapters deal, in a similar vein, with the ambiguities of Galileo's atomism; with icons, models, and symbols in Galileo's Copernican propaganda; and with the image of Galileo in the astronomical writings of John Wilkins .Such details are fascinating and important for understanding Galileo's work and its aftermath, and so Nonnoi's book is useful for contributing such necessary spadework—in particular, the bibliographical documentation is especially valuable and the analysis of the pictures found in the works discussed shows considerable originality. Regrettably, Nonnoi does not integrate such details into an overarching thesis that might elaborate their significance; thus, the work of assimilating them remains to be done. (shrink)

RESUMENInforme bibliográfico de las obras de Maurice Merleau-Ponty hasta 1996, que revisa y actualiza repertorios anteriores. El informe incluye también trabajos inéditos y documentos de su legado personal.PALABRAS CLAVEMERLEAU-PONTY-FILOSOFIA FRANCESA-FENOMENOLOGIAABSTRACTBibliographical report of Maurice Merleau-Ponry's works up to 1996, wich revises and updates previous bibliographies. The report also includes unpublished papers and documents from his personal legacy. KEYWORDSMERLEAU-PONTY- FRENCH PHILOSOPHY-PHENOMENOLOGY.

Guizot aprendió el oficio de historiador preparando con su esposa,Pauline de Meulan, una edición crítica en francés de _Decline and Fall_ de Gibbon. Las personalidades históricas de Gibbon y Guizot fueron muy distintas. También sus respectivos “estilos de historia”. Pero en las obras de Guizot, en especial en su _Historia de la civilización en Europa_, es reconocible el legado de Gibbon. Así, en la eliminación de la barrera entre historia civil y historia religiosa, en la amplitud temática, en la (...) ambición cronológica y en una idea de Europa concebida como algo más que la suma de sus partes. Asimismo en la adopción de la misma palabra _civilización_ y en el hecho de que la interpretación guizotiana de la historia europea hunda sus raíces en tres factores presentes en Gibbon: lo que sobrevivió de las instituciones romanas, el impacto del cristianismo y el aporte germánico. (shrink)

El estudio de la obra de Aristóteles es imprescindible para acercarnos al modo en que Heidegger responde a la pregunta de qué es el tiempo1. El objetivo de la presente comunicación es, en primer lugar, analizar la peculiar radicalización del concepto de tiempo aristotélico efectuada por el joven Heidegger; en segundo lugar, mostrar la estrecha relación entre la comprensión vulgar del tiempo ofrecida por Aristóteles y el tiempo originario, centrándonos en el papel que tiene el momento temporal del futuro en (...) la constitución de nuestro propio ser. (shrink)

John Rawls ha manifestado en diversas ocasiones que su justicia como equidad es una teoría contractualista inspirada en la obra de J. Locke, J. J. Rousseau e I. Kant. Sin embargo, en el desarrollo de su visión sobre la justicia es posible encontrar huellas de otros filósofos como es el caso de la obra David Hume. En este artículo, se estudia la inserción de tres conceptos del naturalismo del filósofo escoces en la deontología moral que sustenta la justicia como equidad: (...) las “circunstancias de la justica”, el “sentido de la justicia” y el “deber natural de justicia”. (shrink)

This article focuses on some aspects of the prophetic veneration through a very specific sub-genre of ḥadīth literature, the so-called ḥadīth musalsal or chained prophetic transmission. Musalsal is the name given to the ḥadīth that in each of the links in the chain of transmission repeat identical expressions or sayings. Often, these expressions refer to a certain ritual or gesture that goes together with the delivery of the saying to the prophet. This article therefore deals with a ritualized transmission in (...) which the fundamental point is how that ḥadīth is transmitted and who transmits it. The chronological framework I have chosen is that of the Naṣrid Kingdom of Granada, even though this study must be a continuation of other works on prophetic veneration during the Almoravid and Almohad periods, the time of the introduction and consolidation of this genre in the Iberian Peninsula and the North Africa. I have collected the authors and transmitters of musalsalāt in al-Andalus from the end of the 7th/ 13th century until the conquest of Granada, and I have shown that their interest in these ḥadīth-s is related to a general interest in the literature of prophetic veneration and the jihād literature. Finally, I have shown that this ritualization process becomes an identity question among the pious Andalusian ulama, which contributes to increasing their pre stige and integrating them into a privileged group of experts. (shrink)

Ya en su tesis doctoral, Malabou (1996) empieza a elaborar, a partir de una relectura de Hegel, una noción que recorrerá toda su obra: el concepto de “plasticidad”. En este artículo analizamos las principales apariciones de dicho concepto en los primeros trabajos de la autora francesa. En ella, dialoga especialmente, y de manera declarada, con Hegel, Heidegger y Derrida, prometiendo un concepto de la esencia o la forma que incorpore la diferencia sin negarla. Si bien el concepto de “plasticidad” en (...) la obra de Malabou ha sufrido un giro, según el cual ha entrado en un diálogo abierto con la biología y, más concretamente, con las neurociencias contemporáneas, en el presente artículo veremos su estatuto antes de dicho giro. (shrink)